ITGB1 antibody (PE)
Quick Overview for ITGB1 antibody (PE) (ABIN2567467)
Target
See all ITGB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain.
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Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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Storage
- 4 °C
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Storage Comment
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- ITGB1 (Integrin beta 1 (ITGB1))
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Alternative Name
- CD29
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Background
- The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain. It is expressed broadly on endothelial cells, epithelial, leukocytes, and smooth muscle. CD29 forms the VLA 1-6 complexes through the non-covalent interaction with the alpha integrins of CD49 a-f. The HMb1-1 antibody is capable of inhibiting T cell proliferation and blocking cell adhesion.
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Gene ID
- 16412, 24511
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UniProt
- P09055
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Pathways
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
Target
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